12/2/2023 0 Comments Witchfire brew multiple curses![]() ProteinRNA interactions are emerging as an important functional element in the regulation of gene expression.Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9:102–114.Glisovic T, Bachorik JL, Yong J, Dreyfuss G (2008) RNA-binding proteins and post-transcriptional gene regulation.Berger SL (2002) Histone modifications in transcriptional regulation.How to publish with us, including Open Access Journal metrics 2.989 (2021) Impact factor 2. Yoon JH, Abdelmohsen K, Gorospe M (2013) Posttranscriptional gene regulation by long noncoding RNA. ![]() Rinn JL, Chang HY (2012) Genome regulation by long noncoding RNAs.Yoon JH, Abdelmohsen K, Gorospe M (2014) Functional interactions among microRNAs and long noncoding RNAs.Cross-linking of proteins to RNA by UV irradiation followed by immunoprecipitation (CLIP) has provided a crucial tool for research in this field. UV cross-linking and immunoprecipitation (CLIP), followed by high-throughput sequencing, is a powerful biochemical assay that maps in vivo protein-RNA interactions on a genome-wide scale.Riley KJ, Steitz JA (2013) The “Observer Effect” in genome-wide surveys of protein-RNA interactions. Lin RJ (2008) RNA -protein interaction protocols. 1.Kudla G, Granneman S, Hahn D, Beggs JD, Tollervey D (2011) Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast.König J, Zarnack K, Rot G, Curk T, Kayikci M, Zupan B, Turner DJ, Luscombe NM, Ule J (2010) iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution.Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M Jr, Jungkamp AC, Munschauer M, Ulrich A, Wardle GS, Dewell S, Zavolan M, Tuschl T (2010) Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.Chi SW, Zang JB, Mele A, Darnell RB (2009) Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, Darnell JC, Darnell RB (2009) HITS-CLIP yields genome-wide insights into brain alternative RNA processing.Ule J, Jensen KB, Ruggiu M, Mele A, Ule A, Darnell RB (2003) CLIP identifies Nova-regulated RNA networks in the brain.Mukherjee N, Corcoran DL, Nusbaum JD, Reid DW, Georgiev S, Hafner M, Ascano M Jr, Tuschl T, Ohler U, Keene JD (2011) Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.Tenenbaum SA, Carson CC, Lager PJ, Keene JD (2000) Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays.The CLIP Tool Kit (CTK) aims at providing a set of tools for flexible, streamlined and comprehensive CLIP data analysis.To a firebug, “kill it with fire” is much more than just a saying, it is an obsession.Īrtificer Class is from Tasha’s Cauldron of Everything and Eberron: Rising from the Last WarĪrt credits: Todor Hristov, Zach Winkler, Sorana-Elena Corbu, Josef Panes These crazed gadgeteers create wondrous (and often extremely dangerous) machinations that use the magic of artifice to manipulate heat, light, and sound. ![]() Firebugs instead turn to magical inventions for this purpose. For evokers, the ability to control fire is the result of countless hours of study. To some people, such as fire genasi and draconic sorcerers, this manifests as an innate power that comes naturally. Since the dawn of civilization, humanity has sought a way to tame the wild power of fire. ![]()
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